Computational investigation of potential dosing schedules for a switch of medication from warfarin to rivaroxaban—an oral, direct Factor Xa inhibitor

The long-lasting anticoagulant effect of vitamin K antagonists can be problematic in cases of adverse drug reactions or when patients are switched to another anticoagulant therapy. The objective of this study was to examine in silico the anticoagulant effect of rivaroxaban, an oral, direct Factor Xa...

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書目詳細資料
發表在:Front Physiol
Main Authors: Burghaus, Rolf, Coboeken, Katrin, Gaub, Thomas, Niederalt, Christoph, Sensse, Anke, Siegmund, Hans-Ulrich, Weiss, Wolfgang, Mueck, Wolfgang, Tanigawa, Takahiko, Lippert, Jörg
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2014
主題:
Physiology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224077/
https://ncbi.nlm.nih.gov/pubmed/25426077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00417
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