Computational investigation of potential dosing schedules for a switch of medication from warfarin to rivaroxaban—an oral, direct Factor Xa inhibitor

The long-lasting anticoagulant effect of vitamin K antagonists can be problematic in cases of adverse drug reactions or when patients are switched to another anticoagulant therapy. The objective of this study was to examine in silico the anticoagulant effect of rivaroxaban, an oral, direct Factor Xa...

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Vydáno v:Front Physiol
Hlavní autoři: Burghaus, Rolf, Coboeken, Katrin, Gaub, Thomas, Niederalt, Christoph, Sensse, Anke, Siegmund, Hans-Ulrich, Weiss, Wolfgang, Mueck, Wolfgang, Tanigawa, Takahiko, Lippert, Jörg
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014
Témata:
Physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224077/
https://ncbi.nlm.nih.gov/pubmed/25426077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00417
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