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Contribution of rivaroxaban to the international normalized ratio when switching to warfarin for anticoagulation as determined by simulation studies
AIM: This study evaluated the influence of rivaroxaban 20 mg once daily on international normalized ratio (INR) during the co-administration period when switching from rivaroxaban to warfarin. METHODS: We developed a calibrated coagulation model that was qualified with phase I clinical data. Prothro...
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| Publicado no: | Br J Clin Pharmacol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4456128/ https://ncbi.nlm.nih.gov/pubmed/25510952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12571 |
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