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Contribution of rivaroxaban to the international normalized ratio when switching to warfarin for anticoagulation as determined by simulation studies

AIM: This study evaluated the influence of rivaroxaban 20 mg once daily on international normalized ratio (INR) during the co-administration period when switching from rivaroxaban to warfarin. METHODS: We developed a calibrated coagulation model that was qualified with phase I clinical data. Prothro...

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Bibliografski detalji
Izdano u:Br J Clin Pharmacol
Glavni autori: Siegmund, Hans-Ulrich, Burghaus, Rolf, Kubitza, Dagmar, Coboeken, Katrin
Format: Artigo
Jezik:Inglês
Izdano: BlackWell Publishing Ltd 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456128/
https://ncbi.nlm.nih.gov/pubmed/25510952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12571
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