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Identification of Extracellular Signal-regulated Kinase 1 (ERK1) Direct Substrates using Stable Isotope Labeled Kinase Assay-Linked Phosphoproteomics

Kinase mediated phosphorylation signaling is extensively involved in cellular functions and human diseases, and unraveling phosphorylation networks requires the identification of substrates targeted by kinases, which has remained challenging. We report here a novel proteomic strategy to identify the...

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發表在:Mol Cell Proteomics
Main Authors: Xue, Liang, Wang, Pengcheng, Cao, Pianpian, Zhu, Jian-kang, Tao, W. Andy
格式: Artigo
語言:Inglês
出版: The American Society for Biochemistry and Molecular Biology 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223502/
https://ncbi.nlm.nih.gov/pubmed/25022875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.O114.038588
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