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Identification of Extracellular Signal-regulated Kinase 1 (ERK1) Direct Substrates using Stable Isotope Labeled Kinase Assay-Linked Phosphoproteomics

Kinase mediated phosphorylation signaling is extensively involved in cellular functions and human diseases, and unraveling phosphorylation networks requires the identification of substrates targeted by kinases, which has remained challenging. We report here a novel proteomic strategy to identify the...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Xue, Liang, Wang, Pengcheng, Cao, Pianpian, Zhu, Jian-kang, Tao, W. Andy
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223502/
https://ncbi.nlm.nih.gov/pubmed/25022875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.O114.038588
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