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Identification of Extracellular Signal-regulated Kinase 1 (ERK1) Direct Substrates using Stable Isotope Labeled Kinase Assay-Linked Phosphoproteomics

Kinase mediated phosphorylation signaling is extensively involved in cellular functions and human diseases, and unraveling phosphorylation networks requires the identification of substrates targeted by kinases, which has remained challenging. We report here a novel proteomic strategy to identify the...

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Vydáno v:Mol Cell Proteomics
Hlavní autoři: Xue, Liang, Wang, Pengcheng, Cao, Pianpian, Zhu, Jian-kang, Tao, W. Andy
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223502/
https://ncbi.nlm.nih.gov/pubmed/25022875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.O114.038588
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