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Interplay between Sumoylation and Phosphorylation for Protection against α-Synuclein Inclusions
Parkinson disease is associated with the progressive loss of dopaminergic neurons from the substantia nigra. The pathological hallmark of the disease is the accumulation of intracytoplasmic inclusions known as Lewy bodies that consist mainly of post-translationally modified forms of α-synuclein. Whe...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4223324/ https://ncbi.nlm.nih.gov/pubmed/25231978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.559237 |
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