Identification of Two Novel Peptides That Inhibit α-Synuclein Toxicity and Aggregation

Aggregation of α-synuclein (αSyn) into proteinaceous deposits is a pathological hallmark of a range of neurodegenerative diseases including Parkinson’s disease (PD). Numerous lines of evidence indicate that the accumulation of toxic oligomeric and prefibrillar αSyn species may underpin the cellular...

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Pubblicato in:Front Mol Neurosci
Autori principali: Popova, Blagovesta, Wang, Dan, Rajavel, Abirami, Dhamotharan, Karthikeyan, Lázaro, Diana F., Gerke, Jennifer, Uhrig, Joachim F., Hoppert, Michael, Outeiro, Tiago F., Braus, Gerhard H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072481/
https://ncbi.nlm.nih.gov/pubmed/33912013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2021.659926
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