Cargando...

MAGE proteins regulate KRAB zinc finger transcription factors and KAP1 E3 ligase activity

Expression of Melanoma AntiGen Encoding (MAGE) genes, particularly MAGE-A3, has been correlated with aggressive clinical course, the acquisition of resistance to chemotherapy and poor clinical outcomes of melanoma and other malignancies. MAGE proteins bind to KAP1, a gene repressor and ubiquitin E3...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Arch Biochem Biophys
Autores principales: Xiao, Tony Z, Suh, Yewseok, Longley, B Jack
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221552/
https://ncbi.nlm.nih.gov/pubmed/25107531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2014.07.026
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!