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MAGE I Transcription Factors Regulate KAP1 and KRAB Domain Zinc Finger Transcription Factor Mediated Gene Repression

Class I MAGE proteins (MAGE I) are normally expressed only in developing germ cells but are aberrantly expressed in many cancers. They have been shown to promote tumor survival, aggressive growth, and chemoresistance but the underlying mechanisms and MAGE I functions have not been fully elucidated....

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Detalhes bibliográficos
Main Authors: Xiao, Tony Z., Bhatia, Neehar, Urrutia, Raul, Lomberk, Gwen A., Simpson, Andrew, Longley, B. Jack
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158099/
https://ncbi.nlm.nih.gov/pubmed/21876767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023747
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