Targeting IL-6 by both passive or active immunization strategies prevents bleomycin-induced skin fibrosis

INTRODUCTION: Interleukin-6 (IL-6) is a pleiotropic cytokine for which preliminary data have suggested that it might contribute to systemic sclerosis (SSc). Our aims were to investigate, firstly, IL-6 expression in patients with SSc and, secondly, the efficacy of both passive and active immunization...

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Vydáno v:Arthritis Res Ther
Hlavní autoři: Desallais, Lucille, Avouac, Jérôme, Fréchet, Maxime, Elhai, Muriel, Ratsimandresy, Rojo, Montes, Matthieu, Mouhsine, Hadley, Do, Hervé, Zagury, Jean-François, Allanore, Yannick
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220089/
https://ncbi.nlm.nih.gov/pubmed/25059342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4672
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