Predicting Potential Endocrine Disrupting Chemicals Binding to Estrogen Receptor α (ERα) Using a Pipeline Combining Structure-Based and Ligand-Based in Silico Methods

por Sellami, Asma, Montes, Matthieu, Lagarde, Nathalie
Publicado en Int J Mol Sci (2021)

Discriminating agonist and antagonist ligands of the nuclear receptors using 3D-pharmacophores

por Lagarde, Nathalie, Delahaye, Solenne, Zagury, Jean-François, Montes, Matthieu
Publicado en J Cheminform (2016)

Hits Discovery on the Androgen Receptor: In Silico Approaches to Identify Agonist Compounds

por Réau, Manon, Lagarde, Nathalie, Zagury, Jean-François, Montes, Matthieu
Publicado en Cells (2019)

Decoys Selection in Benchmarking Datasets: Overview and Perspectives

por Réau, Manon, Langenfeld, Florent, Zagury, Jean-François, Lagarde, Nathalie, Montes, Matthieu
Publicado en Front Pharmacol (2018)

FAF-Drugs: free ADME/tox filtering of compound collections

por Miteva, Maria A., Violas, Stephanie, Montes, Matthieu, Gomez, David, Tuffery, Pierre, Villoutreix, Bruno O.
Publicado 2006

Predictiveness curves in virtual screening

por Empereur-mot, Charly, Guillemain, Hélène, Latouche, Aurélien, Zagury, Jean-François, Viallon, Vivian, Montes, Matthieu
Publicado en J Cheminform (2015)

Immunization against an IL-6 peptide induces anti-IL-6 antibodies and modulates the Delayed-Type Hypersensitivity reaction in cynomolgus monkeys

por Desallais, Lucille, Bouchez, Caroline, Mouhsine, Hadley, Moreau, Gabriel, Ratsimandresy, Rojo, Montes, Matthieu, Do, Hervé, Quintin-Colonna, Françoise, Zagury, Jean-François
Publicado en Sci Rep (2016)

Targeting IL-6 by both passive or active immunization strategies prevents bleomycin-induced skin fibrosis

por Desallais, Lucille, Avouac, Jérôme, Fréchet, Maxime, Elhai, Muriel, Ratsimandresy, Rojo, Montes, Matthieu, Mouhsine, Hadley, Do, Hervé, Zagury, Jean-François, Allanore, Yannick
Publicado en Arthritis Res Ther (2014)

High-resolution mining of the SARS-CoV-2 main protease conformational space: supercomputer-driven unsupervised adaptive sampling

por Jaffrelot Inizan, Théo, Célerse, Frédéric, Adjoua, Olivier, El Ahdab, Dina, Jolly, Luc-Henri, Liu, Chengwen, Ren, Pengyu, Montes, Matthieu, Lagarde, Nathalie, Lagardère, Louis, Monmarché, Pierre, Piquemal, Jean-Philip
Publicado en Chem Sci (2021)

Identification of Genes Whose Expression Profile Is Associated with Non-Progression towards AIDS Using eQTLs

por Spadoni, Jean-Louis, Rucart, Pierre, Le Clerc, Sigrid, van Manen, Daniëlle, Coulonges, Cédric, Ulveling, Damien, Laville, Vincent, Labib, Taoufik, Taing, Lieng, Delaneau, Olivier, Montes, Matthieu, Schuitemaker, Hanneke, Noirel, Josselin, Zagury, Jean-François
Publicado en PLoS One (2015)

Neuropilin 1 and Neuropilin 2 gene invalidation or pharmacological inhibition reveals their relevance for the treatment of metastatic renal cell carcinoma

por Dumond, Aurore, Brachet, Etienne, Durivault, Jérôme, Vial, Valérie, Puszko, Anna K., Lepelletier, Yves, Montemagno, Christopher, Pagnuzzi-Boncompagni, Marina, Hermine, Olivier, Garbay, Christiane, Lagarde, Nathalie, Montes, Matthieu, Demange, Luc, Grépin, Renaud, Pagès, Gilles
Publicado en J Exp Clin Cancer Res (2021)

New CXCR1/CXCR2 inhibitors represent an effective treatment for kidney or head and neck cancers sensitive or refractory to reference treatments

por Dufies, Maeva, Grytsai, Oleksandr, Ronco, Cyril, Camara, Oumar, Ambrosetti, Damien, Hagege, Anaïs, Parola, Julien, Mateo, Lou, Ayrault, Marion, Giuliano, Sandy, Grépin, Renaud, Lagarde, Nathalie, Montes, Matthieu, Auberger, Patrick, Demange, Luc, Benhida, Rachid, Pagès, Gilles
Publicado en Theranostics (2019)

Identification of an in vivo orally active dual-binding protein-protein interaction inhibitor targeting TNFα through combined in silico/in vitro/in vivo screening

por Mouhsine, Hadley, Guillemain, Hélène, Moreau, Gabriel, Fourati, Najla, Zerrouki, Chouki, Baron, Bruno, Desallais, Lucille, Gizzi, Patrick, Ben Nasr, Nesrine, Perrier, Julie, Ratsimandresy, Rojo, Spadoni, Jean-Louis, Do, Hervé, England, Patrick, Montes, Matthieu, Zagury, Jean-François
Publicado en Sci Rep (2017)

SCREENING LOW FREQUENCY SNPS FROM GENOME WIDE ASSOCIATION STUDY REVEALS A NEW RISK ALLELE FOR PROGRESSION TO AIDS

por Le Clerc, Sigrid, Coulonges, Cédric, Delaneau, Olivier, Van Manen, Danielle, Herbeck, Joshua T., Limou, Sophie, An, Ping, Martinson, Jeremy J., Spadoni, Jean-Louis, Therwath, Amu, Veldink, Jan H., van den Berg, Leonard H., Taing, Lieng, Labib, Taoufik, Mellak, Safa, Montes, Matthieu, Delfraissy, Jean-François, Schächter, François, Winkler, Cheryl, Froguel, Philippe, Mullins, James I., Schuitemaker, Hanneke, Zagury, Jean-François
Publicado 2011

Multicohort Genomewide Association Study Reveals a New Signal of Protection Against HIV-1 Acquisition

por Limou, Sophie, Delaneau, Olivier, van Manen, Daniëlle, An, Ping, Sezgin, Efe, Le Clerc, Sigrid, Coulonges, Cédric, Troyer, Jennifer L., Veldink, Jan H., van den Berg, Leonard H., Spadoni, Jean-Louis, Taing, Lieng, Labib, Taoufik, Montes, Matthieu, Delfraissy, Jean-François, Schachter, François, O’Brien, Stephen J., Buchbinder, Susan, van Natta, Mark L., Jabs, Douglas A., Froguel, Philippe, Schuitemaker, Hanneke, Winkler, Cheryl A., Zagury, Jean-François
Publicado 2012

Multiple-cohort genetic association study reveals CXCR6 as a new chemokine receptor involved in long-term nonprogression to AIDS

por Limou, Sophie, Coulonges, Cédric, Herbeck, Joshua T., van Manen, Daniëlle, An, Ping, Le Clerc, Sigrid, Delaneau, Olivier, Diop, Gora, Taing, Lieng, Montes, Matthieu, van't Wout, Angélique B., Gottlieb, Geoffrey S., Therwath, Amu, Rouzioux, Christine, Delfraissy, Jean-François, Lelièvre, Jean-Daniel, Lévy, Yves, Hercberg, Serge, Dina, Christian, Phair, John, Donfield, Sharyne, Goedert, James J., Buchbinder, Susan, Estaquier, Jérôme, Schächter, François, Gut, Ivo, Froguel, Philippe, Mullins, James I., Schuitemaker, Hanneke, Winkler, Cheryl, Zagury, Jean-François
Publicado 2010