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Immunization against an IL-6 peptide induces anti-IL-6 antibodies and modulates the Delayed-Type Hypersensitivity reaction in cynomolgus monkeys

Interleukin-6 (IL-6) overproduction has been involved in the pathogenesis of several chronic inflammatory diseases and the administration of an anti-IL-6 receptor monoclonal antibody has been proven clinically efficient to treat them. However, the drawbacks of monoclonal antibodies have led our grou...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Desallais, Lucille, Bouchez, Caroline, Mouhsine, Hadley, Moreau, Gabriel, Ratsimandresy, Rojo, Montes, Matthieu, Do, Hervé, Quintin-Colonna, Françoise, Zagury, Jean-François
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726013/
https://ncbi.nlm.nih.gov/pubmed/26782790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19549
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