Development of a Delayed-Type Hypersensitivity (DTH) Model in the Cynomolgus Monkey

Although a T-dependent antibody response (TDAR) assay is generally recommended as the first-line immune function assay in nonclinical immunotoxicity evaluation, second-line assays such as delayed-type hypersensitivity (DTH) to measure cell-mediated responses can provide helpful additional informatio...

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Dettagli Bibliografici
Autori principali: Bouchez, Caroline, Gervais, Fréderic, Fleurance, Renaud, Palate, Bernard, Legrand, Jean-Jacques, Descotes, Jacques
Natura: Artigo
Lingua:Inglês
Pubblicazione: Japanese Society of Toxicologic Pathology 2012
Soggetti:
Technical Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392902/
https://ncbi.nlm.nih.gov/pubmed/22907986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.25.183
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