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Development of a Delayed-Type Hypersensitivity (DTH) Model in the Cynomolgus Monkey
Although a T-dependent antibody response (TDAR) assay is generally recommended as the first-line immune function assay in nonclinical immunotoxicity evaluation, second-line assays such as delayed-type hypersensitivity (DTH) to measure cell-mediated responses can provide helpful additional informatio...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Japanese Society of Toxicologic Pathology
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3392902/ https://ncbi.nlm.nih.gov/pubmed/22907986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.25.183 |
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