Targeting Costimulatory Pathways in Systemic Sclerosis

Systemic sclerosis (SSc) is an autoimmune T-cell disease that is characterized by pathological fibrosis of the skin and internal organs. SSc is considered a prototype condition for studying the links between autoimmunity and fibrosis. Costimulatory pathways such as CD28/CTLA-4, ICOS-B7RP1, CD70-CD27...

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Huvudupphovsmän: Gonçalo Boleto, Yannick Allanore, Jérôme Avouac
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2018-12-01
Serie:Frontiers in Immunology
Ämnen:
adaptive immunity
inflammation
costimulatory pathways
systemic sclerosis
fibrosis
Länkar:https://www.frontiersin.org/article/10.3389/fimmu.2018.02998/full
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