Deciphering clonality in aneuploid breast tumors using SNP array and sequencing data

Intra-tumor heterogeneity concerns the existence of genetically different subclones within the same tumor. Single sample quantification of heterogeneity relies on precise determination of chromosomal copy numbers throughout the genome, and an assessment of whether identified mutation variant allele...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Lönnstedt, Ingrid M, Caramia, Franco, Li, Jason, Fumagalli, Debora, Salgado, Roberto, Rowan, Andrew, Salm, Max, Kanu, Nnennaya, Savas, Peter, Horswell, Stuart, Gade, Stephan, Loibl, Sibylle, Neven, Patrick, Sotiriou, Christos, Swanton, Charles, Loi, Sherene, Speed, Terence P
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220069/
https://ncbi.nlm.nih.gov/pubmed/25270265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0470-7
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