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Deciphering clonality in aneuploid breast tumors using SNP array and sequencing data

Intra-tumor heterogeneity concerns the existence of genetically different subclones within the same tumor. Single sample quantification of heterogeneity relies on precise determination of chromosomal copy numbers throughout the genome, and an assessment of whether identified mutation variant allele...

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Podrobná bibliografie
Vydáno v:Genome Biol
Hlavní autoři: Lönnstedt, Ingrid M, Caramia, Franco, Li, Jason, Fumagalli, Debora, Salgado, Roberto, Rowan, Andrew, Salm, Max, Kanu, Nnennaya, Savas, Peter, Horswell, Stuart, Gade, Stephan, Loibl, Sibylle, Neven, Patrick, Sotiriou, Christos, Swanton, Charles, Loi, Sherene, Speed, Terence P
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220069/
https://ncbi.nlm.nih.gov/pubmed/25270265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0470-7
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