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Protection of Armadillo/β-Catenin by Armless, a Novel Positive Regulator of Wingless Signaling

The Wingless (Wg/Wnt) signaling pathway is essential for metazoan development, where it is central to tissue growth and cellular differentiation. Deregulated Wg pathway activation underlies severe developmental abnormalities, as well as carcinogenesis. Armadillo/β-Catenin plays a key role in the Wg...

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Bibliografske podrobnosti
izdano v:PLoS Biol
Main Authors: Reim, Gerlinde, Hruzova, Martina, Goetze, Sandra, Basler, Konrad
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219662/
https://ncbi.nlm.nih.gov/pubmed/25369031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001988
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