Caricamento...
Wingless/β-catenin signaling as a modulator of chemoresistance in cancer
O6-methylguanine-DNA methyltransferase (MGMT) is a DNA repair enzyme involved in chemoresistance. We have shown that MGMT abundance is regulated by canonical Wingless (Wnt) signaling and that inhibition of Wnt signaling restores chemosensitivity in preclinical cancer models. These findings have dire...
Salvato in:
| Pubblicato in: | Mol Cell Oncol |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2016
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4905426/ https://ncbi.nlm.nih.gov/pubmed/27308637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1131356 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|