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The role of the cysteine-rich domain of Frizzled in Wingless-Armadillo signaling
The Frizzled (Fz) receptors contain seven transmembrane helices and an amino-terminal cysteine-rich domain (CRD) that is sufficient and necessary for binding of the ligands, the Wnts. Recent genetic experiments have suggested, however, that the CRD is dispensable for signaling. We engineered fz CRD...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1276175/ https://ncbi.nlm.nih.gov/pubmed/16163385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600817 |
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