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The cysteine-rich frizzled domain of Frzb-1 is required and sufficient for modulation of Wnt signaling

Convincing evidence has accumulated to identify the Frizzled proteins as receptors for the Wnt growth factors. In parallel, a number of secreted frizzled-like proteins with a conserved N-terminal frizzled motif have been identified. One of these proteins, Frzb-1, binds Wnt-1 and Xwnt-8 proteins and...

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Detalhes bibliográficos
Main Authors: Lin, Keming, Wang, Shouwen, Julius, Martin A., Kitajewski, Jan, Moos, Malcolm, Luyten, Frank P.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23413/
https://ncbi.nlm.nih.gov/pubmed/9326585
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