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Biochemical characterization of Wnt-Frizzled interactions using a soluble, biologically active vertebrate Wnt protein

Biochemical studies of Wnt signaling have been hampered by difficulties in obtaining large quantities of soluble, biologically active Wnt proteins. In this paper, we report the production in Drosophila S2 cells of biologically active Xenopus Wnt8 (XWnt8). Epitope- or alkaline phosphatase-tagged XWnt...

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Detalhes bibliográficos
Main Authors: Hsieh, Jen-Chih, Rattner, Amir, Smallwood, Philip M., Nathans, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22330/
https://ncbi.nlm.nih.gov/pubmed/10097073
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