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Biochemical characterization of Wnt-Frizzled interactions using a soluble, biologically active vertebrate Wnt protein

Biochemical studies of Wnt signaling have been hampered by difficulties in obtaining large quantities of soluble, biologically active Wnt proteins. In this paper, we report the production in Drosophila S2 cells of biologically active Xenopus Wnt8 (XWnt8). Epitope- or alkaline phosphatase-tagged XWnt...

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Hlavní autoři: Hsieh, Jen-Chih, Rattner, Amir, Smallwood, Philip M., Nathans, Jeremy
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 1999
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC22330/
https://ncbi.nlm.nih.gov/pubmed/10097073
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