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Evidence that the cysteine-rich domain of Drosophila Frizzled family receptors is dispensable for transducing Wingless

Members of the Frizzled family of serpentine transmembrane receptors are required to transduce Wingless/Int (Wnt) signals and contain in their N-terminal regions a conserved Wnt-binding cysteine-rich domain (CRD). Each CRD has specific affinities for particular Wnts, and it is generally believed tha...

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Detalhes bibliográficos
Principais autores: Chen, Chiann-mun, Strapps, Walter, Tomlinson, Andrew, Struhl, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC528772/
https://ncbi.nlm.nih.gov/pubmed/15514021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407103101
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