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Cysteine-rich domains related to Frizzled receptors and Hedgehog-interacting proteins

Frizzled and Smoothened are homologous seven-transmembrane proteins functioning in the Wnt and Hedgehog signaling pathways, respectively. They harbor an extracellular cysteine-rich domain (FZ-CRD), a mobile evolutionary unit that has been found in a number of other metazoan proteins and Frizzled-lik...

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Detalhes bibliográficos
Main Authors: Pei, Jimin, Grishin, Nick V
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537238/
https://ncbi.nlm.nih.gov/pubmed/22693159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2105
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