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Crystal Structure of the Frizzled-like Cysteine-rich Domain of the Receptor Tyrosine Kinase MuSK

Muscle-specific kinase (MuSK) is an essential receptor tyrosine kinase for establishment and maintenance of the neuromuscular junction (NMJ). Activation of MuSK by agrin, a neuronally derived heparan-sulfate proteoglycan, and LRP4, the agrin receptor, leads to clustering of acetylcholine receptors o...

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Detalhes bibliográficos
Main Authors: Stiegler, Amy L., Burden, Steven J., Hubbard, Stevan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754272/
https://ncbi.nlm.nih.gov/pubmed/19664639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.07.091
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