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Crystal Structure of the Frizzled-like Cysteine-rich Domain of the Receptor Tyrosine Kinase MuSK
Muscle-specific kinase (MuSK) is an essential receptor tyrosine kinase for establishment and maintenance of the neuromuscular junction (NMJ). Activation of MuSK by agrin, a neuronally derived heparan-sulfate proteoglycan, and LRP4, the agrin receptor, leads to clustering of acetylcholine receptors o...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2754272/ https://ncbi.nlm.nih.gov/pubmed/19664639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.07.091 |
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