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The Cytoplasmic Adapter-Protein Dok7 Activates the Receptor Tyrosine Kinase MuSK via Dimerization
Formation of the vertebrate neuromuscular junction requires, among others proteins, Agrin, a neuronally derived ligand, and the following muscle proteins: LRP4, the receptor for Agrin; MuSK, a receptor tyrosine kinase (RTK); and Dok7, a cytoplasmic adapter protein. Dok7 comprises a pleckstrin-homolo...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2917201/ https://ncbi.nlm.nih.gov/pubmed/20603078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.06.007 |
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