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The Cytoplasmic Adapter-Protein Dok7 Activates the Receptor Tyrosine Kinase MuSK via Dimerization

Formation of the vertebrate neuromuscular junction requires, among others proteins, Agrin, a neuronally derived ligand, and the following muscle proteins: LRP4, the receptor for Agrin; MuSK, a receptor tyrosine kinase (RTK); and Dok7, a cytoplasmic adapter protein. Dok7 comprises a pleckstrin-homolo...

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Autors principals: Bergamin, Elisa, Hallock, Peter T., Burden, Steven J., Hubbard, Stevan R.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917201/
https://ncbi.nlm.nih.gov/pubmed/20603078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.06.007
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