Kinase domain of the muscle-specific receptor tyrosine kinase (MuSK) is sufficient for phosphorylation but not clustering of acetylcholine receptors: Required role for the MuSK ectodomain?

Formation of the neuromuscular junction (NMJ) depends upon a nerve-derived protein, agrin, acting by means of a muscle-specific receptor tyrosine kinase, MuSK, as well as a required accessory receptor protein known as MASC. We report that MuSK does not merely play a structural role by demonstrating...

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Bibliografiska uppgifter
Huvudupphovsmän: Glass, David J., Apel, Elizabeth D., Shah, Sonal, Bowen, David C., DeChiara, Thomas M., Stitt, Trevor N., Sanes, Joshua R., Yancopoulos, George D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences of the USA 1997
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC23162/
https://ncbi.nlm.nih.gov/pubmed/9238066
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