Kinase domain of the muscle-specific receptor tyrosine kinase (MuSK) is sufficient for phosphorylation but not clustering of acetylcholine receptors: Required role for the MuSK ectodomain?

Formation of the neuromuscular junction (NMJ) depends upon a nerve-derived protein, agrin, acting by means of a muscle-specific receptor tyrosine kinase, MuSK, as well as a required accessory receptor protein known as MASC. We report that MuSK does not merely play a structural role by demonstrating...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Glass, David J., Apel, Elizabeth D., Shah, Sonal, Bowen, David C., DeChiara, Thomas M., Stitt, Trevor N., Sanes, Joshua R., Yancopoulos, George D.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23162/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9238066/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.16.8848
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