TM-05 PTEN INDUCED KINASE1 (PINK1) NEGATIVELY REGULATES AEROBIC GLYCOLYSIS IN GLIOBLASTOMA

Aggressive cancer cells are characterized by high rates glycolysis and lactate production, a metabolic reprogramming event known as the Warburg effect. This ultimately provides tumor cells including GBM the most malignant and common primary brain tumor with intermediate metabolites for anabolic proc...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Golbourn, Brian, Agnihotri, Sameer, Remke, Marc, Cairins, Rob, Smith, Christian, Mackenzie, Danielle, Fuller, Gregory, Taylor, Michael, Hawkins, Cynthia, Zadeh, Gelareh, Rutka, James
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218629/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou278.5
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