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SC-21 TRIM3, A HUMAN ORTHOLOG OF DROSOPHILA BRAT, MAINTAINS ASYMMETRIC CELL DIVISION OF GLIOMA STEM CELLS BY REGULATING c-MYC AND NOTCH1
Glioma stem cells, capable of self-renewal and multipotent differentiation, influence neoplastic growth by a dynamic balance between symmetric and asymmetric cell division. Growth is favored by a shift to symmetric division in which greater numbers of self-renewing cells emerge, as opposed to asymme...
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| Publicat a: | Neuro Oncol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4218581/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou275.21 |
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