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SC-21 TRIM3, A HUMAN ORTHOLOG OF DROSOPHILA BRAT, MAINTAINS ASYMMETRIC CELL DIVISION OF GLIOMA STEM CELLS BY REGULATING c-MYC AND NOTCH1

Glioma stem cells, capable of self-renewal and multipotent differentiation, influence neoplastic growth by a dynamic balance between symmetric and asymmetric cell division. Growth is favored by a shift to symmetric division in which greater numbers of self-renewing cells emerge, as opposed to asymme...

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Bibliografiset tiedot
Julkaisussa:Neuro Oncol
Päätekijät: Mukherjee, Subhas, Chen, Gang, Kong, Jun, Brat, Daniel
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218581/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou275.21
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