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Human Brat ortholog TRIM3 is a tumor suppressor that regulates asymmetric cell division in glioblastoma

Cancer stem cells, capable of self-renewal and multipotent differentiation, influence tumor behavior through a complex balance of symmetric and asymmetric cell divisions. Mechanisms regulating the dynamics of stem cells and their progeny in human cancer are poorly understood. In Drosophila, mutation...

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Detalhes bibliográficos
Main Authors: Chen, Gang, Kong, Jun, Tucker-Burden, Carol, Anand, Monika, Rong, Yuan, Rahman, Fahima, Moreno, Carlos S, Van Meir, Erwin G., Hadjipanayis, Constantinos G., Brat, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134737/
https://ncbi.nlm.nih.gov/pubmed/24947043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3703
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