Asymmetric cell division promotes therapeutic resistance in glioblastoma stem cells

Asymmetric cell division (ACD) enables the maintenance of a stem cell population while simultaneously generating differentiated progeny. Cancer stem cells (CSCs) undergo multiple modes of cell division during tumor expansion and in response to therapy, yet the functional consequences of these divisi...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:JCI Insight
Main Authors: Hitomi, Masahiro, Chumakova, Anastasia P., Silver, Daniel J., Knudsen, Arnon M., Pontius, W. Dean, Murphy, Stephanie, Anand, Neha, Kristensen, Bjarne W., Lathia, Justin D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2021
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934841/
https://ncbi.nlm.nih.gov/pubmed/33351787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.130510
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