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TRIM8 regulates stemness in glioblastoma through PIAS3‐STAT3

Glioblastoma (GBM) is the most malignant form of primary brain tumor, and GBM stem‐like cells (GSCs) contribute to the rapid growth, therapeutic resistance, and clinical recurrence of these fatal tumors. STAT3 signaling supports the maintenance and proliferation of GSCs, yet regulatory mechanisms ar...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Zhang, Changming, Mukherjee, Subhas, Tucker‐Burden, Carol, Ross, James L., Chau, Monica J., Kong, Jun, Brat, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5332279/
https://ncbi.nlm.nih.gov/pubmed/28100038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12034
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