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IT-21 PD-1 BLOCKADE SHOWS SYNERGISTIC SURVIVAL, ANTI-TUMOR IMMUNE RESPONSE AND LONG-TERM MEMORY WITH INTERSTITIAL BUT NOT SYSTEMIC CHEMOTHERAPY: STUDY IN A MURINE GLIOBLASTOMA MODEL
INTRODUCTION: Glioblastoma is the most malignant brain tumor and is characterized by resistance to current therapies. Multi-modal treatment holds potential for complete tumor eradication, however the combination of chemotherapy and immunotherapy has been avoided due to concerns over possible mutuall...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4218237/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou258.19 |
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