Anti-PD-1 Blockade and Stereotactic Radiation Produce Long-Term Survival in Mice With Intracranial Gliomas

PURPOSE: Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults, and radiation is one of the main treatment modalities. However, cure rates remain low despite best available therapies. Immunotherapy is a promising modality that could work synergistically with radiation, which...

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Detalhes bibliográficos
Main Authors: Zeng, Jing, See, Alfred P., Phallen, Jillian, Jackson, Christopher M., Belcaid, Zineb, Ruzevick, Jacob, Durham, Nicholas, Meyer, Christian, Harris, Timothy J., Albesiano, Emilia, Pradilla, Gustavo, Ford, Eric, Wong, John, Hammers, Hans-Joerg, Mathios, Dimitris, Tyler, Betty, Brem, Henry, Tran, Phuoc T., Pardoll, Drew, Drake, Charles G., Lim, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963403/
https://ncbi.nlm.nih.gov/pubmed/23462419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2012.12.025
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