GE-09 TERT PROMOTER MUTATION, IDH MUTATION AND 1p/19q CODELETION DEFINE FIVE GLIOMA MOLECULAR GROUPS WITH SPECIFIC CLINICAL CHARACTERISTICS AND GERMLINE VARIANT ASSOCIATIONS

Defining homogenous etiologic and clinical subgroups of infiltrative glioma by grade and histology has been challenging. We hypothesized that TERT promoter mutation, IDH mutation and 1p/19q codeletion in grade II-IV gliomas will generate clinically-homogeneous groups that are enriched for other acqu...

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Detaylı Bibliyografya
Asıl Yazarlar: Eckel-Passow, Jeanette, Lachance, Daniel, Walsh, Kyle, Decker, Paul, Sicotte, Hugues, Pekmezci, Melike, Molinaro, Annette, Rice, Terri, Kosel, Matt, Smirnov, Ivan, Sarkar, Gobinda, Caron, Alissa, Kollmeyer, Thomas, Giannini, Caterina, Huse, Jason, Tihan, Tarik, Wiemels, Joseph, Wiencke, John, Wrensch, Margaret, Jenkins, Robert
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2014
Konular:
Abstracts
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218213/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou256.9
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