GENE-29. DLL3 AND ETV1 ARE INACTIVATED/METHYLATED IN CIC WILD-TYPE, IDH-MUTATED, 1p/19q-CODELETED GLIOMA

Adult diffuse glioma that harbor IDH mutation and 1p/19q codeletion commonly have CIC mutations; however, the functional and prognostic significance of CIC mutations remains unclear. We hypothesized that when CIC is not mutated, other genes may be inactivated by hypermethylation. Identifying such ge...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Neuro Oncol
Главные авторы: Kosel, Matthew, Lachance, Daniel, Decker, Paul, Kollmeyer, Thomas, Caron, Alissa, Drucker, Kristen, Sarkar, Gobinda, Knight, Andrew, Halder, Chandralekha, Tian, Shulan, Abyzov, Alexej, Burns, Terry, Giannini, Caterina, Eckel-Passow, Jeanette, Jenkins, Robert
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2018
Предметы:
Abstracts
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216778/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.455
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы