GENE-29. DLL3 AND ETV1 ARE INACTIVATED/METHYLATED IN CIC WILD-TYPE, IDH-MUTATED, 1p/19q-CODELETED GLIOMA

Adult diffuse glioma that harbor IDH mutation and 1p/19q codeletion commonly have CIC mutations; however, the functional and prognostic significance of CIC mutations remains unclear. We hypothesized that when CIC is not mutated, other genes may be inactivated by hypermethylation. Identifying such ge...

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Publicado no:Neuro Oncol
Main Authors: Kosel, Matthew, Lachance, Daniel, Decker, Paul, Kollmeyer, Thomas, Caron, Alissa, Drucker, Kristen, Sarkar, Gobinda, Knight, Andrew, Halder, Chandralekha, Tian, Shulan, Abyzov, Alexej, Burns, Terry, Giannini, Caterina, Eckel-Passow, Jeanette, Jenkins, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216778/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.455
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