ET-17 TRANSIENT FASTING ENHANCES REPLICATION AND THERAPEUTIC ACTIVITY OF ONCOLYTIC HSV IN GLIOBLASTOMA THERAPY

BACKGROUND AND OBJECTIVE: Short term fasting has been shown to enhance efficacy of chemotherapy by sensitizing tumor cells and protecting normal cells in a variety of cancer models including glioblastoma (GBM). Malignant cells, unlike normal cells, respond to fasting by promoting oncogenic signaling...

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Main Authors: Esaki, Shinichi, Rabkin, Samuel D., Martuza, Robert L., Wakimoto, Hiroaki
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218112/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou255.17
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