AT-22 PHASE II TRIAL OF BEVACIZUMAB, RADIATION THERAPY (RT) AND TEMOZOLOMIDE FOLLOWED BY BEVACIZUMAB AND TEMOZOLOMIDE WITH CONTINUATION OF BEVACIZUMAB BEYOND PROGRESSION

BACKGROUND: Two multicenter phase III trials, RTOG0825 and AVAglio, evaluated the addition of bevacizumab to RT and temozolomide in newly diagnosed glioblastoma patients and demonstrated a lack of statistically significant increased survival. In both studies, the majority of patients discontinued be...

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Main Authors: Ghiaseddin, Ashley, Dunn-Pirio, Anastasie, Peters, Katherine, Vlahovic, Gordana, Herndon, James, Threatt, Stevie, Sampson, John, Friedman, Allan, Friedman, Henry, Desjardins, Annick
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217800/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou237.22
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