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AT-22 PHASE II TRIAL OF BEVACIZUMAB, RADIATION THERAPY (RT) AND TEMOZOLOMIDE FOLLOWED BY BEVACIZUMAB AND TEMOZOLOMIDE WITH CONTINUATION OF BEVACIZUMAB BEYOND PROGRESSION
BACKGROUND: Two multicenter phase III trials, RTOG0825 and AVAglio, evaluated the addition of bevacizumab to RT and temozolomide in newly diagnosed glioblastoma patients and demonstrated a lack of statistically significant increased survival. In both studies, the majority of patients discontinued be...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4217800/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou237.22 |
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