Molecular Profiling of Patient-Matched Brain and Extracranial Melanoma Metastases Implicates the PI3K Pathway as a Therapeutic Target

PURPOSE: An improved understanding of the molecular pathogenesis of brain metastases, one of the most common and devastating complications of advanced melanoma, may identify and prioritize rational therapeutic approaches for this disease. In particular, the identification of molecular differences be...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Clin Cancer Res
Egile Nagusiak: Chen, Guo, Chakravarti, Nitin, Aardalen, Kimberly, Lazar, Alexander J., Tetzlaff, Michael T., Wubbenhorst, Bradley, Kim, Sang-Bae, Kopetz, Scott, Ledoux, Alicia A., Gopal, Y.N. Vashisht, Pereira, Cristiano Goncalves, Deng, Wanleng, Lee, Ju-Seog, Nathanson, Katherine L., Aldape, Kenneth D., Prieto, Victor G., Stuart, Darrin, Davies, Michael A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216765/
https://ncbi.nlm.nih.gov/pubmed/24803579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-3003
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak