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Polymorphisms in the carcinogen detoxification genes CYB5A and CYB5R3 and breast cancer risk in African American women

PURPOSE: Cytochrome b(5) (encoded by CYB5A) and NADH cytochrome b(5) reductase (encoded by CYB5R3) detoxify aromatic and heterocyclic amine mammary carcinogens found in cigarette smoke. We hypothesized that CYB5A and CYB5R3 polymorphisms would be associated with breast cancer risk in women. METHODS:...

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Detalhes bibliográficos
Main Authors: Blanke, Kristina L., Sacco, James C., Millikan, Robert C., Olshan, Andrew F., Luo, Jingchun, Trepanier, Lauren A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216608/
https://ncbi.nlm.nih.gov/pubmed/25225034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10552-014-0454-7
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