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A single nucleotide polymorphism in the canine cytochrome b(5) reductase (CYB5R3) gene is associated with sulfonamide hypersensitivity and is overrepresented in Doberman Pinschers
Canine sulfonamide hypersensitivity (HS) has been associated with a variant in the cytochrome b(5) reductase gene (CYB5R3 729A>G), which encodes a drug-detoxifying enzyme. Study objectives were to determine variant allele frequency in Doberman Pinschers (DOBE), a breed which may be predisposed to...
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| Publicado no: | J Vet Pharmacol Ther |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5932251/ https://ncbi.nlm.nih.gov/pubmed/29336038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jvp.12478 |
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