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Individual Variability in the Detoxification of Carcinogenic Arylhydroxylamines in Human Breast

Cytochrome b(5) (b5) and NADH cytochrome b(5) reductase (b5R) detoxify reactive hydroxylamine (NHOH) metabolites of known arylamine and heterocyclic amine mammary carcinogens. The aim of this study was to determine whether NHOH reduction for the prototypic arylamine 4-aminobiphenyl (4-ABP) was prese...

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Detalhes bibliográficos
Main Authors: Rhoads, Keelia, Sacco, James C., Drescher, Nicholas, Wong, Amos, Trepanier, Lauren A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098962/
https://ncbi.nlm.nih.gov/pubmed/21447608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr073
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