Anticholinergic drugs rescue synaptic plasticity in DYT1 dystonia: role of M(1) muscarinic receptors

BACKGROUND: Broad spectrum muscarinic receptor antagonists have represented the first available treatment for different movement disorders such as dystonia. However, the specificity of these drugs and their mechanism of action is not entirely clear. METHODS: We performed a systematic analysis of the...

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Main Authors: Maltese, M., Martella, G., Madeo, G., Fagiolo, I., Tassone, A., Ponterio, G., Sciamanna, G., Burbaud, P., Conn, P.J., Bonsi, P., Pisani, A.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216601/
https://ncbi.nlm.nih.gov/pubmed/25195914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.26009
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